Paul S Myles Selected Research

Nitrous Oxide (Laughing Gas)

7/2022	Safety of Nitrous Oxide Anesthesia in a Selected Group of Patients Undergoing Neurosurgery: An Exploratory Subgroup Analysis of the ENIGMA Trials.
5/2016	Severe Nausea and Vomiting in the Evaluation of Nitrous Oxide in the Gas Mixture for Anesthesia II Trial.
12/2015	Nitrous Oxide and Serious Long-term Morbidity and Mortality in the Evaluation of Nitrous Oxide in the Gas Mixture for Anaesthesia (ENIGMA)-II Trial.
10/2014	The safety of addition of nitrous oxide to general anaesthesia in at-risk patients having major non-cardiac surgery (ENIGMA-II): a randomised, single-blind trial.
11/2011	Chronic postsurgical pain after nitrous oxide anesthesia.
2/2011	Nitrous oxide and long-term morbidity and mortality in the ENIGMA trial.
3/2009	Nitrous oxide and perioperative cardiac morbidity (ENIGMA-II) Trial: rationale and design.
8/2007	Avoidance of nitrous oxide for patients undergoing major surgery: a randomized controlled trial.

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Paul S Myles Research Topics

Disease

12	Myocardial Infarction 07/2022 - 10/2002
11	Pain (Aches) 01/2022 - 04/2002
10	Stroke (Strokes) 07/2022 - 08/2007
7	Vomiting 07/2022 - 08/2007
7	Nausea 01/2021 - 12/2002
6	Hemorrhage 03/2022 - 03/2014
6	Hypotension (Low Blood Pressure) 01/2022 - 10/2002
6	Surgical Wound Infection 05/2021 - 10/2002
4	Infections 07/2022 - 07/2016
4	Pneumonia (Pneumonitis) 07/2022 - 08/2007
4	Coronary Artery Disease (Coronary Atherosclerosis) 01/2022 - 03/2009
4	Respiratory Insufficiency (Respiratory Failure) 01/2022 - 04/2002
4	Wounds and Injuries (Trauma) 05/2021 - 10/2002
4	Heart Failure 10/2020 - 10/2006
3	Heart Arrest (Cardiac Arrest) 07/2022 - 03/2014
3	Sepsis (Septicemia) 01/2022 - 10/2017
3	Postoperative Pain 01/2022 - 11/2011
3	COVID-19 01/2022 - 01/2020
3	Chest Pain (Chest Pains) 12/2021 - 01/2021
3	Unstable Angina 10/2021 - 07/2016
3	Postoperative Nausea and Vomiting (PONV) 01/2021 - 05/2016
3	Neoplasms (Cancer) 01/2020 - 03/2011
3	Wound Infection (Wound Infections) 11/2018 - 10/2002
3	Cardiovascular Diseases (Cardiovascular Disease) 11/2018 - 10/2006
2	Venous Thromboembolism 07/2022 - 08/2007
2	Iron Deficiencies 07/2022 - 01/2021
2	Pneumothorax 07/2022 - 08/2007
2	Opioid-Related Disorders (Opiate Addiction) 01/2022 - 04/2019
2	Critical Illness (Critically Ill) 01/2022 - 07/2016
2	Myocardial Ischemia (Ischemic Heart Diseases) 12/2021 - 03/2009
2	Chronic Pain 04/2019 - 11/2011
2	Thrombosis (Thrombus) 01/2019 - 01/2019
2	Pulmonary Embolism 11/2018 - 08/2007
2	Acute Kidney Injury (Acute Renal Failure) 06/2018 - 10/2015
2	Cardiac Tamponade 12/2017 - 01/2016
2	Primary Graft Dysfunction 11/2014 - 01/2013
1	Fever (Fevers) 07/2022
1	Inflammation (Inflammations) 03/2022
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2022
1	Infarction (Infarctions) 12/2021
1	Cognitive Dysfunction 11/2021
1	Non-ST Elevated Myocardial Infarction 10/2021
1	Drug-Related Side Effects and Adverse Reactions 01/2021
1	ST Elevation Myocardial Infarction 01/2021
1	Anemia 01/2021
1	Diabetes Mellitus 01/2021
1	Acute Coronary Syndrome 01/2021

Drug/Important Bio-Agent (IBA)

9	Analgesics (Analgesic Drugs)IBA 01/2022 - 09/2008
8	Nitrous Oxide (Laughing Gas)IBA 07/2022 - 08/2007
8	Opioid Analgesics (Opioids)IBA 01/2022 - 02/2003
6	Tranexamic Acid (AMCA)FDA Link 03/2022 - 12/2017
5	Biomarkers (Surrogate Marker)IBA 12/2021 - 04/2004
4	Fentanyl (Sublimaze)FDA LinkGeneric 10/2021 - 10/2002
4	Fibrinolysin FDA Link 05/2021 - 01/2019
3	Lidocaine (Xylocaine)FDA LinkGeneric 01/2022 - 01/2021
3	Antifibrinolytic Agents (Antifibrinolytics)IBA 04/2021 - 01/2019
3	Pharmaceutical PreparationsIBA 01/2020 - 12/2002
3	AntiemeticsIBA 05/2016 - 12/2002
2	Transferrin (beta 2 Transferrin)IBA 07/2022 - 01/2021
2	IronIBA 07/2022 - 01/2021
2	Ferritins (Ferritin)IBA 07/2022 - 01/2021
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2021 - 01/2019
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2019 - 10/2002
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2019 - 01/2016
2	Oxygen (Dioxygen)IBA 07/2016 - 04/2004
2	Anesthetics (Anesthetic Agents)IBA 05/2016 - 03/2010
2	Prostaglandins DIBA 11/2014 - 01/2013
2	Tramadol (K315)FDA LinkGeneric 09/2008 - 12/2002
1	C-Reactive ProteinIBA 07/2022
1	Mitochondrial DNA (mtDNA)IBA 03/2022
1	Leukocyte Elastase (Neutrophil Elastase)IBA 03/2022
1	SmokeIBA 01/2022
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2022
1	Creatine Kinase (Creatine Phosphokinase)IBA 12/2021
1	Troponin IIBA 12/2021
1	TicagrelorIBA 10/2021
1	Lysine (L-Lysine)FDA Link 04/2021
1	GlucocorticoidsIBA 01/2021
1	Hemoglobins (Hemoglobin)IBA 01/2021

Therapy/Procedure

12	Length of Stay 07/2022 - 08/2007
6	Therapeutics 01/2021 - 10/2002
5	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 03/2022 - 06/2006
4	Artificial Respiration (Mechanical Ventilation) 01/2022 - 11/2018
4	Anesthesia 08/2017 - 03/2009
4	Epidural Analgesia 03/2011 - 04/2002
3	Analgesia 12/2021 - 04/2002
3	Critical Care (Surgical Intensive Care) 01/2021 - 08/2007
2	Blood Transfusion (Blood Transfusions) 07/2022 - 05/2021
2	Fluid Therapy (Oral Rehydration Therapy) 06/2019 - 03/2012
2	Activities of Daily Living (ADL) 01/2019 - 03/2015
2	Sternotomy 10/2018 - 09/2008
2	Lung Transplantation 11/2014 - 01/2013
2	Resuscitation 01/2008 - 03/2004
1	Heart-Assist Devices 01/2022
1	Vascular Surgical Procedures 01/2022
1	Nerve Block (Nerve Blocks) 01/2022
1	Percutaneous Coronary Intervention 12/2021
1	Mechanical Ventilators (Ventilator) 01/2021
1	Respiratory Protective Devices (Gas Mask) 01/2021
1	Airway Management 01/2021